Destroy All Humans! vs Destroy All Humans! 2
Side-by-side comparison of features, pricing, ratings, and alternatives.
Set in 1959 America, Destroy All Humans! lets you play as Cryptosporidium 137, a Furon spy tasked with collecting human DNA to fuel your species' cloning program. The game blends open‑world exploration, over‑the‑top weapons, and tongue‑in‑cheek humor to parody Cold War era culture.
Assume the role of Crypto, the human‑hating alien, in this sci‑fi action‑adventure spoof. Explore an expanded open world filled with secret agents, giant creatures, Soviet forces, and ninja warriors while wreaking havoc. Use alien powers, a variety of weapons, and humor‑filled dialogue to exact revenge on humanity for destroying your mothership. The game offers both single‑player and co‑operative modes for up to two players.
- Unique alien protagonist with humorous motives
- Large open‑world environments to explore
- Varied weapon and ability upgrades
- Strong period‑specific satire and humor
- Large, varied open world to explore
- Entertaining humor and satire
- Co‑operative mode adds replay value
- Wide selection of alien weapons and powers
- Graphics are dated by modern standards
- Some mission objectives can feel repetitive
- Limited replayability after story completion
- Graphics are dated by modern standards
- Some mission objectives can feel repetitive
- Limited multiplayer options beyond co‑op
More alternatives & similar tools
Alternatives to Destroy All Humans!
View all →
Groovy alien chaos meets 1970s kung fu in a comedic open‑world shooter.

Cause chaos in 1975 with alien powers and a wicked sense of humor
Alternatives to Destroy All Humans! 2
View all →
Groovy alien chaos meets 1970s kung fu in a comedic open‑world shooter.

Cause chaos in 1975 with alien powers and a wicked sense of humor
The Verdict
AI-generated from listing dataBoth games cost the same and offer similar retro action‑adventure humor, but Destroy All Humans! 2 adds co‑op play and a broader weapon set, making it the better choice for players who want more multiplayer replay value.
Key differences
- •Setting: A is 1950s USA, B is 1970s USA.
- •Co‑op: A is single‑player only, B supports two‑player co‑op.
- •Weapon variety: B lists a wider arsenal including classic Zap‑O‑Matic and more alien weapons.
- •Critic score: A 70/100, B 75/100.
- •Multiplayer options: A none, B includes co‑op mode.
Gameplay & fun factor
B adds co‑op and a wider weapon selection, increasing variety and fun beyond A's single‑player focus.
Platform availability
No platform data provided for either title.
Price & value
Both priced at $19.99 with one‑time purchase.
Multiplayer / co‑op
B supports single‑player and co‑op; A is single‑player only.
Content & replayability
B's co‑op mode and larger weapon pool give higher replay potential than A.
Difficulty & accessibility
No difficulty or accessibility information supplied.
Graphics & performance
Both described as having dated graphics; no performance differences noted.
Choose Destroy All Humans! if…
Fans who prefer a 1950s setting and single‑player story without co‑op.
Choose Destroy All Humans! 2 if…
Players who want co‑op, more weapons, and slightly higher critical reception.
Common questions
Do both games cost the same?
Yes, each has an MSRP of $19.99 as a one‑time purchase.
Is there any multiplayer in Destroy All Humans! (2005)?
No, it is single‑player only.
Which title has a higher critic score?
Destroy All Humans! 2 has a critic score of 75/100, compared to 70/100 for the original.

