Synfig Studio

Spine

Spine, made by Esoteric Software, is dedicated 2D skeletal animation software: artists rig flat artwork onto bones, apply mesh deformation and weighting, and pose characters with inverse kinematics rather than hand-drawing every frame. A dopesheet and ghosting tools support precise timing and motion review during animation. Animations export through Spine's own runtime libraries, which cover "nearly every major game toolkit and programming language," so a rig built once can be driven live inside a game rather than exported as baked video or sprite sheets. Spine runs on Windows, Mac, and Linux and is sold as perpetual Essential and Professional licenses, plus Enterprise and Education tiers.

Moho

Moho is professional 2D animation software focused on drawing, rigging, and animating characters efficiently. It combines vector drawing tools optimized for animation with an advanced 2D rigging system supporting forward and inverse kinematics, letting animators reuse rigged characters across scenes instead of redrawing frame by frame. The software is sold under a perpetual licensing model with no required subscription, and is offered in two editions: Moho Pro for professionals and Moho Debut for hobbyists and first-time animators. It supports physics simulation, distortion meshes, a graph editor for precise timing control, and exports to game engines including Unreal, Unity, and Godot as well as Blender.

Krotos Studio

Krotos Studio is sound design software from audio company Krotos built around Video-to-Sound technology: it analyzes a video clip and automatically generates matching sound effects drawn from real recordings, rather than synthesizing artificial audio. It includes a royalty-free sound effects library that updates monthly and real-time XY-pad performance controls for shaping sounds live. Krotos Studio runs as a standalone application on Mac and Windows and as a VST/AU/AAX plugin inside DAWs and video editors, with full support in Pro Tools, Ableton Live, and Reaper, and partial support in Logic Pro, Cubase, Nuendo, Studio One, and DaVinci Resolve. It's aimed at video editors, sound designers, composers, and content creators working in film, games, and other media production who need fast Foley and effects without manual sound library digging.